I first asked about screen reader support before reason 12 then again after its release. As reason 12 has less screen reader support than previous versions. Although I'm working on a speech web ui to work with reason remote, this is limited as there is no remote control over midi, pitch or rex editing, no remote control over the CV/Audio rooting, browser or tool window and incomplete remote control over the sequencer and transport.
The better option is to add screen reader support to the DAW directly. Other DAWs have done work on this, including protools and logic for mac, reaper on windows and now ableton live. NI have done work for their komplete keyboards and now their maschine.
It would be great to see reason open it's DAW to screen reader users and in the mean while I'll keep working on the speech web ui.